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Carole AbelCA

Average response time: 1 hour

About Carole

I am a former Vice President, Programs & Portfolio Office, with over 20 years of leadership experience in biotech and pharmaceutical environments.

Today, I operate as a Fractional Chief of Staff and Portfolio & Governance Executive, partnering with biotech CEOs, founders and Boards at critical inflection points.

I step in when:
• Portfolio complexity outpaces structure
• Capital discipline becomes decisive
• Execution credibility must be restored

My role is to bring executive alignment, governance clarity and milestone-driven prioritisation without adding bureaucracy.

I operate as an embedded executive partner, not an external consultant.
  • French

    Native or bilingual

  • English

    Native or bilingual

  • German

    Conversational

  • Spanish

    Conversational

Can work on-site
Bâle (up to 50km)

Experience

  • enAbel Consulting
    Founder & Fractional Executive
    BIOTECH
    June 2025 - Today (1 year)
    Bâle, Switzerland
    Independent executive advisory platform supporting biotech leadership teams in governance structuring, portfolio prioritization and executive execution alignment.

    Selected Mandate:
    Synendos Therapeutics (CH)
    Head of Development (Fractional Executive Mandate – 6 months)
    • Acted as executive integrator between CEO, CMO, CCO and development teams
    • Provided strategic development oversight during critical corporate phase
    • Structured decision frameworks and cross-functional alignment mechanisms
    • Reinforced portfolio focus and milestone discipline in capital-sensitive context
    • Ensured executive visibility across development priorities and resource allocation
    Fractional Leadership Biotechnology Program Leadership Portfolio Strategy Strategic Planning & Execution
  • MindMed (now Definium Therapeutics) - Biotech (US/CH)
    VP, Head of Programs and Portfolio Office
    BIOTECH
    September 2020 - May 2025 (4 years and 8 months)
    Zoug, Switzerland
    Former executive leader responsible for portfolio governance, cross-functional execution alignment and milestone-driven delivery in a fast-scaling biotech environment.

    Reported to Executive Leadership and worked closely with Board-level stakeholders during critical growth and capital allocation phases.

    Scope of responsibility:
    • Built and led the Programs & Portfolio Office
    • Designed portfolio governance and decision frameworks
    • Established milestone-driven prioritisation across clinical programs
    • Strengthened executive-level risk visibility and escalation mechanisms
    • Aligned cross-functional teams (Clinical, Regulatory, CMC, Finance) around strategic development milestones

    Strategic impact:
    • Increased execution predictability across pipeline programs
    • Reduced decision latency at the executive level
    • Improved portfolio transparency under capital pressure
    • Enhanced cross-functional accountability and milestone discipline
    Executive Leadership Portfolio Strategy Portfolio Governance Cross-functional Team Leadership Organizational Design
  • Creso Pharma – Biotech
    Head of Operations
    BIOTECH
    September 2017 - August 2020 (2 years and 11 months)
    Zug, Switzerland
    Senior operating executive partnering directly with the CEO during a high-growth and corporate structuring phase.

    Responsible for strengthening operational foundations, governance maturity and executive-level coordination across functions.

    Scope of responsibility:
    • Oversaw corporate operations across finance, administration, and external partnerships
    • Contributed to corporate finance structuring and due diligence processes
    • Supported M&A activities and cross-border growth initiatives
    • Strengthened governance processes and executive reporting
    • Drove operational alignment between leadership, external advisors, and investors

    Strategic impact:
    • Increased operational discipline and transparency
    • Improved executive decision support during the expansion phase
    • Enhanced cross-functional coordination and scalability
    Executive Leadership Operational Strategy Corporate Governance Corporate Finance Mergers & Acquisitions

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Education

  • Executive MBA
    EDHEC Business School
    2017
    Executive MBA
  • Master in Project Management
    University of Mulhouse
    2005
    Master

Skill set

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